Precision Dispensing Technology for Microneedle Patches
Scalable precision dispensing for MedTech applications
Microneedle patches are transforming transdermal drug delivery – offering precise, pain-free, and patient-friendly alternatives for medications, vaccines, and diagnostics. However, large-scale production requires more than just formulation expertise – it requires precise and reliable dispensing technology.
At marco System Analysis and Development, we provide precision dispensing systems engineered specifically for the challenges of microneedle patch manufacturing. From development to production, our solutions ensure reliable, scalable, and bubble-free dispensing– even in the smallest volumes.
Your application – our expertise
Our precision dispensing systems are designed to meet the exacting needs of MedTech manufacturers, covering:
- Clean, safe dispensing of active pharmaceutical ingredients (APIs), gels, suspensions, or polymer-based carriers into microneedle cavities
- Multiple material layers (e.g., API at the tips and backing material)
- Bubble-free, contactless on-the-fly jetting
- Repeatability over thousands of cycles
- In-line AI-vision control for 100% cavity inspection
- Cleanroom-compatible integration (GMP, ISO)
Whether you're producing vaccine patches, hormone therapies or wearable biosensors – we support your process with tailored dispensing solutions.
Customised for your process
Every microneedle patch application is unique.
With our modular precision dispensing technology, we develop tailored solutions – configured to your process, materials, and production goals.
From lab to production
Our solutions support every stage of your product development
- Feasibility testing for new formulations or patch layouts
- Pilot production and process validation with scalable set-ups
- Automated integration with modular platforms and precision jetting technology
How it works – On-the-fly jetting into smallest cavities
Our high-frequency micro dispensing technology enables on-the-fly dispensing at up to 100 Hz, with full process transparency and quality control.
Step 1 – API dispensing
A defined volume of active pharmaceutical ingredient (API) is dispensed precisely into the cavity – contactless, precise and bubble-free.
Step 2 – API at the tip
The API sits precisely where it was dispensed: at the tip of the microneedle.
In-line AI Inspection📹
Before the backing is added, each cavity is inspected by an AI-supported camera system - ensuring 100% quality before the next step
Step 3 – Back filling
A second fill adds the backing material – completing the structure of the microneedle patch.
Step 4 – Finished mold
The result: a separated tip and stable backing – ready for curing and demoulding.
Cured microneedle with dyed API and clear backing material
From lab to production – modular systems
Our flexible precision dispensing systems grow with your process – from early R&D to fully automated production:
- Supporting feasibility studies and lab setups with the marc0 Gantry System ↗
- Enabling pilot lines and process validation with modular dispensing units
- Powering high-throughput production using the marc1 Gantry System and scalable multi-valve configurations
- Handling sensor patch assembly and biocompatible material coatings
All systems are designed for seamless integration into your production environment – compact, reliable, and service-friendly.
Why MedTech manufacturers trust marco
- Precision dispensing from micro- to nanolitre scale
- Reliable dispensing of gels, suspensions, APIs
- Scalable throughput with high-speed on-the-fly jetting
- Inline refill and minimal system downtime
- Integrated AI camera for process control
- Reduced material waste and increased yield
- Designed and engineered in Germany
Every dispensing application is different – especially in the medical field.
That’s why we develop precision dispensing solutions tailored to your needs using our modular system architecture. Together with your team, we configure the optimal setup for your process – from valve selection to automation level.
Let’s take your microneedle patch production to the next level
Talk to our experts about your dispensing application.